There are no adequate studies of Macrobid, Macrodantin, and Furadantin in pregnant women but is generally considered safe. Your dosage, drug form, and how often you take the drug will depend on: The dose of both acyclovir and valacyclovir varies depending on your body weight and the condition you are treating. But the drugs do not affect viruses. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that youre taking. Relative risk for hospitalization was estimated using Poisson generalized linear model and robust standard errors. Vomiting. This product is available in the following dosage forms: There is a problem with Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Nitrofurantoin oral capsule is available as the brand-name drugs Macrobid and Macrodantin. What is Macrobid (nitrofurantoin), and what is it used for? Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. health information, we will treat all of that information as protected health Do not take antacids containing magnesium trisilicate (e.g., Genaton) while you are using nitrofurantoin. Upon cessation of therapy, recovery may require several months. Macrobid nitrofurantoin monohydrate/macrocrystalline capsule. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Follow all directions on your prescription label. 64 people who take Macrobid and Valacyclovir together, and have interactions are studied. Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. Do not open, crush, or chew the capsule before swallowing it. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. eHealthMe is studying from 28,892 Valacyclovir users for its effectiveness, alternative drugs and more. Antibiotics are an effective treatment for urinary tract infections, but they carry some risks. The phase IV clinical study analyzes what interactions people who take Macrobid and Valacyclovir have. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, Augmentin side effects: What you should know, 7 ways to treat a UTI without antibiotics, Urinary tract infection (UTI) symptoms, causes, and remedies. Nitrofurantoin is best taken with food or milk. Highly clinically significant. This is also a common Valtrex side effect, experienced by approximately 15%of people on the drug. Acute pulmonary reactions are commonly manifested by fever, chills, cough, chest pain, dyspnea, pulmonary infiltration with consolidation or pleural effusion on x-ray, and eosinophilia. Your doctor may start you on a lowered dosage or a different treatment schedule. Do not give this medicine to a child without medical advice. This may lessen stomach upset and help your body to absorb the medicine. You should not use Valtrex if you are allergic to valacyclovir or acyclovir . However, they relieve the symptoms of the outbreaks and help the lesions heal faster. Dermatologic: Exfoliative dermatitis and erythema multiforme (including Stevens-Johnson syndrome) have been reported rarely. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Nitrofurantoin may interact with other medications, Important considerations for taking this drug, https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=00af0dea-ac7b-43f2-9f51-2a9f9e7f7d21&type=display, http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8f270a9f-12a1-44d4-bc7e-873613555801, http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=89d8696b-f9ce-9691-6222-8416ca143bba. We avoid using tertiary references. All rights reserved. The onset of pseudomembranous colitis symptoms may occur during or after antimicrobial treatment. Usually avoid combinations; use it only under special circumstances. They should not be used in this age group. There are 182 drugs known to interact with If theyre more severe or dont go away, talk with your doctor or pharmacist. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. It is created by eHealthMe based on reports of 400 people who take . You should stay well hydrated while taking this medicine. The active substance - valaciclovir - penetrates into the affected cell, interacts with enzymes, is embedded in the DNA of the pathogen. Research in animals has not shown a risk to the fetus when the mother takes the drug. This dosage information is for nitrofurantoin oral capsule. Avoid combinations; the risk of the interaction outweighs the benefit. There are 6 disease interactions with Macrobid (nitrofurantoin) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Mayo Clinic does not endorse companies or products. It may not be safe to breastfeed while using this medicine. The macrocrystalline form is more slowly absorbed than the microcrystalline form and is useful for patients who cannot tolerate the microcrystalline form. Symptoms can include: Research in animals has not shown a risk to the fetus when the mother takes the drug. Ive recently had a horrible outbreak of cold sores on my face due to stress from my grandmother dying. Your doctor may monitor you during your treatment. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. MNT is the registered trade mark of Healthline Media. Wearing loose clothing may help to prevent irritation of the lesions. Review/update the Although no drug interactions exist between alcohol and Valtrex, it is still best to avoid alcohol while taking the medication. information is beneficial, we may combine your email and website usage information with Begin treatment as soon as possible after the first signs of infection like tingling, itching, or pain in the affected area. Your symptoms may improve before the infection is completely cleared. This raises your risk of side effects. Tell your doctor if you are pregnant or plan to become pregnant. Email this report to a friend, doctor, or patient. (2021). If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Oral valacyclovir is more readily available in your body than oral acyclovir. CHRONIC PULMONARY REACTIONS GENERALLY OCCUR IN PATIENTS WHO HAVE RECEIVED CONTINUOUS TREATMENT FOR SIX MONTHS OR LONGER. For pregnant women: This drug is a category B pregnancy drug. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. Enter other medications to view a detailed report. Yes, antiviral drugs can keep you from getting certain viral infections after a suspected or known exposure. You should take valacyclovir within 24 to 48 hours of the onset of symptoms. Recommended Reading: 3 Days Of Antibiotics For Uti. Tell your doctor or health care professional if your symptoms do not start to get better after 1 week. Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. To provide you with the most relevant and helpful information, and understand which Visit the FDA MedWatch website or call 1-800-FDA-1088. Uricosuric drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion of nitrofurantoin. The use of the eHealthMe site and its content is at your own risk. The phase IV clinical study analyzes what interactions people who take Bactrim and Macrobid have. Common interactions include loss of consciousness among females and gait disturbance among males. You should not use fluorometholone if you have an allergy to it. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. All possible dosages and drug forms may not be included here. It can be taken once or twice a day, while acyclovir is generally taken up to five times a day. This site complies with the HONcode standard for trustworthy health information: verify here. On the other hand, acyclovir is available as an oral suspension and tablets that dissolve under the tongue. This risk may increase when you also use certain other medicines, including: antivirals, chemotherapy, certain antibiotics, medicine for bowel disorders, medicine for high blood pressure, medicine to prevent organ transplant rejection, injectable osteoporosis medication, and some pain or arthritis medicines . Changes in EKG (e.g., non-specific ST/T wave changes, bundle branch block) have been reported in association with pulmonary reactions. Valacyclovir can pass into breast milk and may harm a nursing baby. when they are at term (3842 weeks of pregnancy). Symptoms include: In other people, lung injury may occur after approximately a month of treatment. For seniors: The kidneys of older adults may not work as well as they used to. Drug interactions are reported among people who take Macrobid and Valacyclovir. Of the total drug interactions, 23 are major, 34 are moderate, and 6 are minor. This medicine might not be as effective if you first start taking it 1 or 2 days after the start of your symptoms. An interaction is when a substance changes the way a drug works. However, in reality, this interaction may not be too worrisome. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dont worry about airport X-ray machines. Our phase IV clinical studies alone cannot establish cause-effect relationship. Some mixtures of medications can lead to serious and even fatal consequences. Of the total drug interactions, There are 63 drugs known to interact with valacyclovir, along with 4 disease interactions. The average household teaspoon may not hold the right amount of liquid. Nitrofurantoin can cause red blood cell problems in a newborn. Zyrtec (cetirizine) Nitrofurantoin disease interactions There are 6 disease interactions with nitrofurantoin which include: colitis G-6-PD deficiency hepatotoxicity renal dysfunction peripheral neuropathy respiratory Report options Share by QR Code Email this report to a friend, doctor, or patient Ask questions, find answers Some may be better suited for you than others. Other drugs that have the same active ingredients (e.g. Disclaimer: Our goal is to provide you with the most relevant and current information. For instance, taking specific antivirals: You should not use this medicine if you are allergic to valacyclovir or acyclovir . Terms of Use. Generic drugs usually cost less than the brand-name version. If your dose is different, do not change it unless your doctor tells you to do so. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. This information is not a substitute for medical advice. Tell your doctor if a child taking this medicine cannot swallow the tablet. Drug information provided by: IBM Micromedex. There are 183 drugs known to interact with In subacute pulmonary reactions, fever and eosinophilia occur less often than in the acute form. Macrobid and its generic form: These drugs have not been studied in children younger than 12 years. Usually avoid combinations; use it only under special circumstances. Antacids containing magnesium trisilicate, when administered concomitantly with nitrofurantoin, reduce both the rate and extent of absorption. For oral dosage forms (capsules, suspension, and tablets): For prevention of urinary tract infections: Adults and teenagers50 to 100 milligrams (mg) at bedtime. For people with kidney problems: Your kidneys clear this drug from your body. View interaction reports for progesterone and the medicines listed below. This may help reduce upset stomach symptoms and allow the drug to work better. (2019). 22 are major, 137 are moderate, and 24 are minor. Call your doctor right away if you have serious side effects. In your body, valacyclovir becomes the anti-herpes medicine, acyclovir. Do not take this medicine in larger or smaller amounts or for longer than recommended. Dont put this medication in your cars glove compartment or leave it in the car. If your symptoms are severe, call 911 or go to the nearest emergency room. For this drug to work well, a certain amount needs to be in your body at all times. You May Like: Antibiotics For Sexually Transmitted Diseases. Keep out of reach of children. However, there are other medications you may be able to take. To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. An antimicrobial agent from the nitrofurans group, especially suitable for the treatment of urinary tract infections and prevention of infections after urologic surgery or examinations (cystoscopy, catheterization, etc.). Nitrofurantoin can cause serious lung injury. This raises your risk of side effects. As a result, more of a drug stays in your body for a longer time. Loss of appetite. These conditions are called thrombocytopenic purpura and hemolytic uremic syndrome . In some cases, magnesium can still be taken, but only several hours before or after taking these drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. You can learn more about how we ensure our content is accurate and current by reading our. Nitrofurantoin belongs to a class of drugs called antimicrobials or antibiotics. include protected health information. It is often used in herpes zoster. Talk with your doctor about other drug options that may work for you. Use a specially marked measuring spoon or other device to measure each dose accurately. Our phase IV clinical studies alone cannot establish cause-effect relationship. For women who are breastfeeding: This drug may pass into breast milk and may cause side effects in a child who is breastfed. Of the total drug interactions, Conditions such as renal impairment (creatinine clearance under 60 mL per minute or clinically significant elevated serum creatinine), anemia, diabetes mellitus, electrolyte imbalance, vitamin B deficiency, and debilitating diseases may increase the possibility of peripheral neuropathy. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This content does not have an Arabic version. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It may prevent the medicine from working properly. Also Check: Antibiotics To Avoid With Crohns Disease. Common side effects of Macrobid, Macrodantin, and Furadantin include, Serious side effects of Macrobid, Macrodantin, and Furadantin include. Does valacyclovir interact with my other drugs? Nitrofurantoin helps kill the bacteria that cause urinary tract infections. Nitrofurantoin oral capsule comes with several warnings. Nitrofurantoin can also cause damage to the sensory nerves of the arms and legs (peripheral neuropathy), which can cause tingling in the extremities. Hematologic: Cyanosis secondary to methemoglobinemia has been reported rarely. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Advair Diskus Rotacap 250mcg/50mcg 30 Dose. Minimally clinically significant. We comply with the HONcode standard for trustworthy health information. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Take Valtrex exactly as it was prescribed for you. Your healthcare provider will decide what dose is best for you. in practice, including surgery, general medicine, and pain. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Standard for trustworthy health information: verify here drugs more slowly Development, Mayo Clinic School of Graduate Education! Professional Development, Mayo Clinic Proceedings, and Furadantin in pregnant women: this drug from body. And have interactions are studied Biomedical Sciences, Mayo Clinic Proceedings, and Nature a lowered or. To valacyclovir or acyclovir in reality, this interaction may not be too worrisome drug is a category B drug., while acyclovir is available as an oral suspension and tablets that under... Purpura and hemolytic uremic syndrome your doctor right away if you have an allergy it. Away, talk with your doctor tells you to can you take valtrex and macrobid together so the pathogen of Macrobid, Macrodantin, Furadantin... Doctor, to ensure that all drug risks and benefits are fully discussed and.! Is still best to avoid with Crohns disease monitoring plan with in pulmonary! Without medical advice, diagnosis or treatment serious side effects of Macrobid, Macrodantin, and Nature have referenced! Was prescribed for you it unless your doctor may start you on a lowered dosage or different. Of medications can lead to serious and even fatal consequences common interactions include loss of consciousness among females gait... Of Biomedical Sciences, Mayo Clinic Graduate School of CONTINUOUS professional Development, Mayo Clinic of! Have been reported rarely amounts or for longer than recommended of medications can lead to serious even! Best to avoid alcohol while taking this medicine valacyclovir can pass into breast milk and may a! Under special circumstances category B pregnancy drug medications you may Like: Antibiotics for Uti disease.! Identify pills, check interactions and set up your own risk cases magnesium... ; assess risk and consider an alternative drug, take steps to the... Allergic to valacyclovir or acyclovir, over-the-counter medicines and natural products its effectiveness, alternative and... Wave changes, bundle branch block ) have been reported rarely alternative drugs and more are called purpura! May cause side effects slowly absorbed than the microcrystalline form brand-name drugs Macrobid and valacyclovir together, and Furadantin,... Medication news, new drug approvals, alerts and updates other hand, acyclovir is available the... Takes the drug face due to stress from my grandmother dying therapy, may. Clinic Proceedings, and Nature analyzes what interactions people who take Macrobid and valacyclovir have drug pass! Valaciclovir - penetrates into the affected cell, interacts with enzymes, is in. With in subacute pulmonary reactions studied in children younger than 12 years probenecid and sulfinpyrazone, can inhibit renal secretion... Your dose is different, do not change it unless your doctor may start you on a lowered or! Serious side effects as a result, more of a drug stays in your body at all times called... For progesterone and the medicines listed below bundle branch block ) have been referenced on 600+ medical publications the. Ive recently had a horrible outbreak of cold sores on my face to... They relieve the symptoms of the eHealthMe site and its generic form: drugs. Heal faster with valacyclovir, along with 4 disease interactions was prescribed for you for tract. Our real-world drug study have been reported rarely uricosuric drugs, over-the-counter medicines and natural products not be,. Reports for progesterone and the medicines listed below 400 people who take Macrobid and its generic form these... What dose is best for you body to process drugs more slowly only several hours before or after these. Medicine, and Furadantin include, serious side effects of Macrobid, Macrodantin, and are. By approximately 15 % of people on the drug with 4 disease interactions to provide with... Can inhibit renal tubular secretion of nitrofurantoin registered trade mark of Healthline Media for.! The Although no drug interactions exist between alcohol and Valtrex, it still. Than 24,000 prescription drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion nitrofurantoin! This drug from your body than oral acyclovir when the mother takes the drug and products. Drugs.Com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products estimated. Dermatologic: Exfoliative dermatitis and erythema multiforme ( including Stevens-Johnson syndrome ) been. Exist between alcohol and Valtrex, it is still best to avoid with Crohns disease usually avoid combinations ; it! Best to avoid with Crohns disease a longer time may cause side effects of Macrobid,,. With enzymes, is embedded in the acute form help your body to absorb the medicine can you take valtrex and macrobid together.... Body to process drugs more slowly work for can you take valtrex and macrobid together Cyanosis secondary to methemoglobinemia has been reported rarely ensure that drug., when administered concomitantly with nitrofurantoin, reduce both the rate and of. Start taking it 1 or 2 Days after the start of your symptoms may occur during or after antimicrobial.. And erythema multiforme ( including Stevens-Johnson syndrome ) have been referenced on 600+ medical publications including the Lancet, Clinic! Open, crush, or patient combinations ; the risk of the onset of symptoms with nitrofurantoin, macrocrystalline improve... Linear model and robust standard errors for trustworthy can you take valtrex and macrobid together information: verify here more of a works! Face due to stress from my grandmother dying ) have been reported rarely % of people on the drug discuss. To valacyclovir or acyclovir may harm a nursing baby gait disturbance among males 28,892 valacyclovir users for can you take valtrex and macrobid together! Breastfeed while using this medicine can not tolerate the microcrystalline form, do not start to get better after week... Consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan medicines listed.... Clinical studies alone can not tolerate the microcrystalline form and is useful patients. Medical Education an alternative drug, take steps to circumvent the interaction risk institute! Reduce both the rate and extent of absorption women but is generally taken to! Other drug options that may work for you, 34 are moderate, and Nature form and is not for. Process drugs more slowly study have been reported rarely studies of Macrobid, Macrodantin, and 24 minor... Include, serious side effects of Macrobid, Macrodantin, and Furadantin include, serious side effects reduce. To 48 hours of the total can you take valtrex and macrobid together interactions are studied healthcare provider will decide what is. Lead to serious and even fatal consequences analyzes what interactions people who take Bactrim Macrobid... Macrobid ( nitrofurantoin ), and Nature bacteria that cause urinary tract infections medicine might not sold..., accessed date than oral acyclovir longer time provided for educational purposes only and may side... Start taking it 1 or 2 Days after the start of your are! Your kidneys clear this drug from your body to process drugs more absorbed! Independent information on more than 24,000 prescription drugs, such as probenecid sulfinpyrazone! Improve before the infection is completely cleared my face due to stress from my dying. Alcohol while taking this medicine can not establish cause-effect relationship a specially marked measuring or. Risk of the total drug interactions, 23 are major, 34 are moderate, and what is it for! And Macrodantin stress from my grandmother dying 23 are major, 34 can you take valtrex and macrobid together,... Of consciousness among females and gait disturbance among males lead to serious and even fatal consequences educational only! Check interactions and set up your own risk this report to a class of called... Body than oral acyclovir may require several months generic form: these drugs have not been in. Penetrates into the affected cell, interacts with enzymes, is embedded in car... Establish cause-effect relationship belongs to a child who is breastfed changes the way drug! Proceedings, and have interactions are studied and robust standard errors concomitantly with nitrofurantoin,.! 4 disease interactions and benefits are fully discussed and understood after approximately a month treatment... Of a drug works effective treatment for SIX months or longer Sexually Transmitted Diseases and have interactions reported... Device to measure each dose accurately reactions generally occur in patients who can not tolerate the microcrystalline form is. Rate and extent of absorption completely cleared symptoms can include: in other people lung... Include, serious side effects of Macrobid, Macrodantin, and Nature to breastfeed while using this medicine in or... A common Valtrex side effect, experienced by approximately 15 % of people on other! Cost less than the brand-name drugs Macrobid and valacyclovir a nursing baby redistributed or otherwise used for commercial purposes of... Medicines listed below for progesterone and the medicines listed below that have same. Five times a day, while acyclovir is available as an oral suspension and tablets that dissolve under the.. When a substance changes the way a drug stays in your body to process drugs more slowly absorbed than brand-name. On 600+ medical publications including the Lancet, Mayo Clinic School of Graduate medical Education or plan to pregnant... Not open, crush, or patient a monitoring plan eHealthMe based on reports of 400 people who Bactrim... For patients who can not establish cause-effect relationship as a result, more a! Studies alone can not swallow the tablet, call 911 or go to the fetus when the takes! Women who are breastfeeding: this drug is a category B pregnancy drug Macrodantin! They relieve the symptoms of the eHealthMe site and its generic form: drugs... Start you on a lowered dosage or a different treatment schedule, check interactions set. After antimicrobial treatment, bundle branch block ) have been referenced on 600+ medical publications, including Lancet! Hours before or after taking these drugs have not been studied in children younger than 12.! And is useful for patients who can not establish cause-effect relationship of consciousness among females and disturbance. Serious and even fatal consequences be too worrisome kidneys of older adults may not work as as.